product description:
Benfotiamine raises the blood level of thiamine pyrophosphate (TPP), the biologically active co-enzyme of thiamine. Thiamine and its co-enzyme, TPP thiamine (vitamin B1) plays an essential part in the metabolism of glucose, through actions of it co-enzyme TPP (thiamine pyrophosphate). TPP is formed by the enzymatically catalyzed addition of two phosphate groups donated by ATP to thiamine. TPP also goes by the name thiamine diphosphate. In the cytoplasm of the cell, glucose, a 6-carbon sugar, is metabolized to pyruvic acid, which is converted into acetyl-CoA, otherwise known as active acetate. Acetyl CoA enters the mitochondrion, where it serves as the starting substrate in the Kreb s cycle citric acid cycle. The Krebs cycle is the primary source of cellular metabolic energy. TPP, along with other co-enzymes, is essential for the removal of CO2 from pyruvic acid, which in turn is a key step in the conversion of pyruvic acid to acetyl CoA. CO2 removal from pyruvic acid is called oxidative decarboxylation and for this reason, TPP was originally referred to as cocarboxylase. TPP is thus vital to the cell s energy supply. Benfotiamine helps maintain healthy cells in the presence of blood glucose. Acting as a biochemical super-thiamin, it does this through several different cellular mechanisms, as discussed below. Benfotiamine and glucose metabolism benfotiamine normalizes cellular processes fueled by glucose metabolites. As long as glucose remains at normal levels, excess glucose metabolites do not accumulate within the cell. The bulk of the cell s glucose supply is converted to pyruvic acid, which serves as substrate for production of acetyl CoA, the primary fuel for the krebs cycle. Of the total amount of metabolic energy (in the form of ATP) released from food, the Krebs cycle generates about 90 percent.
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Customer Common Questions & Answers:
Question: You have imported quality products. What is the price of Doctor's Best Benfotiamine 300 with… in Pakistan?
Answer: The pricing of our products is determined by their weight and size. Additionally, fluctuations in the dollar exchange rate in Pakistan may result in changes to our prices. To obtain the most accurate and up-to-date pricing, please check our website or contact our sales representative before placing your order.
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Answer:
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Answer: No, we don't have physical store but you can place your from our office or from online.
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Answer: Yes, we ship in almost all the cities of Pakistan using famous courier & logistic services of Pakistan.
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Answer:Since we import products from USA, Canada, UK or China so it take 3 to 4 weeks. We do our best to make import process fast and smooth and try to deliver ASAP all across Pakistan.
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Answer: Yes! you can do until or unless you can deposit 30% advance using one of our payment methods you can place order from anywhere of world.
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Answer: We always try to buy products using Amazon USA from the brands or official resellers. In case of any confusion we can share amazon or eBay order ID with you so you can check with them directly.
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Answer: Since we buy your products from Amazon USA so you can read product reviews before to orders us. For your convenience, you can find the product review link on all the product pages.
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Answer: We have no product exchange policy. Yes! If you get wrong product or if product not working properly, you can return it within 3 days of delivery.
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Answer: In case your refund approve we try to make sure it within 7 days.
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Answer: If the product you get will be different from the one you order then we will make its 100% refund.
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